Inhibition of myostatin (unknown origin) expressed in HEK293 cells at 0.3 uM after 4 hrs by dual luciferase reporter gene assay relative to (4S)-5-[[(...

ID: ALA4481627

Type: Binding

Description: Inhibition of myostatin (unknown origin) expressed in HEK293 cells at 0.3 uM after 4 hrs by dual luciferase reporter gene assay relative to (4S)-5-[[(1S)-2-[[(1S,2S)-1-[[(1S)-5-amino-1-[[(1S,2S)-1-[[(1S)-4-amino-1-[[(1S,2S)-1-[[(1S,2S)-1-[[(1S)-2-[[(1S)-5-amino-1-[[(1S)-1-[[(1S)-1-[[(1S)-1-carbamoyl-3-methyl-butyl]carbamoyl]-4-guanidino-butyl]carbamoyl]-3-methyl-butyl]carbamoyl]pentyl]amino]-1-(hydroxymethyl)-2-oxo-ethyl]carbamoyl]-2-methyl-butyl]carbamoyl]-2-methyl-butyl]carbamoyl]-4-oxo-butyl]carbamoyl]-2-methyl-butyl]carbamoyl]pentyl]carbamoyl]-2-methyl-butyl]amino]-1-(1H-indol-3-ylmethyl)-2-oxo-ethyl]amino]-4-[[(2S,3S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S,3R)-2-[[(2S)-4-amino-2-[[(2S)-5-amino-2-[[(2S)-5-guanidino-2-[[2-(2-naphthyloxy)acetyl]amino]pentanoyl]amino]-5-oxo-pentanoyl]amino]-4-oxo-butanoyl]amino]-3-hydroxy-butanoyl]amino]-5-guanidino-pentanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]-3-hydroxy-propanoyl]amino]-5-guanidino-pentanoyl]amino]-3-methyl-pentanoyl]amino]-5-oxo-pentanoic acid

Format: BAO_0000219

Organism: Homo sapiens

Cell type: HEK293

Target:  Growth/differentiation factor 8(ALA3407325)

Document:  ALA4480415

Inhibition of myostatin (unknown origin) expressed in HEK293 cells at 0.3 uM after 4 hrs by dual luciferase reporter gene assay relative to (4S)-5-[[(1S)-2-[[(1S,2S)-1-[[(1S)-5-amino-1-[[(1S,2S)-1-[[(1S)-4-amino-1-[[(1S,2S)-1-[[(1S,2S)-1-[[(1S)-2-[[(1S)-5-amino-1-[[(1S)-1-[[(1S)-1-[[(1S)-1-carbamoyl-3-methyl-butyl]carbamoyl]-4-guanidino-butyl]carbamoyl]-3-methyl-butyl]carbamoyl]pentyl]amino]-1-(hydroxymethyl)-2-oxo-ethyl]carbamoyl]-2-methyl-butyl]carbamoyl]-2-methyl-butyl]carbamoyl]-4-oxo-butyl]carbamoyl]-2-methyl-butyl]carbamoyl]pentyl]carbamoyl]-2-methyl-butyl]amino]-1-(1H-indol-3-ylmethyl)-2-oxo-ethyl]amino]-4-[[(2S,3S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S,3R)-2-[[(2S)-4-amino-2-[[(2S)-5-amino-2-[[(2S)-5-guanidino-2-[[2-(2-naphthyloxy)acetyl]amino]pentanoyl]amino]-5-oxo-pentanoyl]amino]-4-oxo-butanoyl]amino]-3-hydroxy-butanoyl]amino]-5-guanidino-pentanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]-3-hydroxy-propanoyl]amino]-5-guanidino-pentanoyl]amino]-3-methyl-pentanoyl]amino]-5-oxo-pentanoic acid: 1