Basic Information
ID: ALA4482010
Type: Binding
Description: Inhibition of human JAK1 using TK-substrate-biotin preincubated for 5 mins followed by substrate addition and further incubated for 30 mins and subsequently measured after 1 hr by HTRF assay
Format: BAO_0000357
Organism: Homo sapiens
Target: Tyrosine-protein kinase JAK1(ALA2835)
Document: ALA4480445
Inhibition of human JAK1 using TK-substrate-biotin preincubated for 5 mins followed by substrate addition and further incubated for 30 mins and subsequently measured after 1 hr by HTRF assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4482010
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 312.38 | 1.54 | 1.54 |
| 443.56 | 3.71 | 3.71 |
| 401.47 | 3.56 | 3.56 |
| 443.51 | 3.52 | 3.52 |
| 445.57 | 3.93 | 3.93 |
| 414.52 | 3.48 | 3.48 |
| 364.41 | 2.57 | 2.57 |
| 349.40 | 2.69 | 2.69 |
| 432.53 | 4.02 | 4.02 |
| 445.57 | 3.93 | 3.93 |
| 349.40 | 2.69 | 2.69 |
| 379.42 | 2.15 | 2.15 |
| 456.55 | 3.44 | 3.44 |
| 363.43 | 3.08 | 3.08 |
| 456.55 | 3.44 | 3.44 |
| 363.40 | 4.10 | 4.10 |
| 444.54 | 4.18 | 4.18 |
| 406.45 | 2.53 | 2.53 |
| 457.58 | 4.10 | 4.10 |
| 430.51 | 3.79 | 3.79 |
| 363.43 | 3.08 | 3.08 |
| 379.42 | 2.15 | 2.15 |
| 430.51 | 3.79 | 3.79 |
| 393.45 | 2.80 | 2.80 |
| 443.56 | 3.71 | 3.71 |
| 414.52 | 3.48 | 3.48 |
| 345.41 | 3.96 | 3.96 |
| 457.58 | 4.10 | 4.10 |
| 472.47 | 4.17 | 4.17 |
| 472.47 | 4.17 | 4.17 |
| 393.45 | 2.80 | 2.80 |