Basic Information
ID: ALA4482018
Type: Binding
Description: Inhibition of IDO1 in IFN-gamma stimulated human HeLa cells assessed as reduction in kynurenine production incubated for 24 hrs relative to control
Format: BAO_0000219
Organism: Homo sapiens
Cell type: HeLa
Target: Indoleamine 2,3-dioxygenase(ALA4685)
Document: ALA4480446
Inhibition of IDO1 in IFN-gamma stimulated human HeLa cells assessed as reduction in kynurenine production incubated for 24 hrs relative to control: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4482018
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 438.24 | 0.42 | 0.42 |
| 473.62 | 7.12 | 7.12 |
| 517.67 | 8.01 | 8.01 |
| 479.55 | 6.81 | 6.81 |
| 493.58 | 7.20 | 7.20 |
| 489.62 | 7.37 | 7.37 |
| 543.73 | 8.92 | 8.92 |
| 493.58 | 7.20 | 7.20 |
| 495.60 | 7.16 | 7.16 |
| 521.63 | 7.84 | 7.84 |
| 544.72 | 8.32 | 8.32 |
| 513.59 | 7.30 | 7.30 |
| 475.59 | 6.98 | 6.98 |
| 511.57 | 7.34 | 7.34 |
| 479.55 | 6.81 | 6.81 |
| 521.63 | 7.84 | 7.84 |
| 481.66 | 7.57 | 7.57 |
| 489.62 | 7.37 | 7.37 |
| 466.58 | 6.49 | 6.49 |
| 482.65 | 6.96 | 6.96 |
| 488.63 | 7.11 | 7.11 |
| 475.59 | 6.98 | 6.98 |
| 508.69 | 7.53 | 7.53 |
| 495.60 | 7.16 | 7.16 |
| 497.54 | 6.95 | 6.95 |
| 491.63 | 7.33 | 7.33 |
| 517.67 | 8.01 | 8.01 |
| 489.62 | 7.37 | 7.37 |
| 517.67 | 8.01 | 8.01 |
| 504.68 | 7.16 | 7.16 |
| 475.59 | 6.98 | 6.98 |
| 482.65 | 6.96 | 6.96 |