Basic Information
ID: ALA4482112
Type: Binding
Description: Inhibition of HDAC in human HeLa nuclear extract using Boc-Lys(Ac)-AMC as substrate preincubated for 5 mins followed by substrate addition and measured after 30 mins by fluorescence assay
Format: BAO_0000219
Organism: Homo sapiens
Cell type: HeLa
Target: Histone deacetylase(ALA2093865)
Document: ALA4480453
Inhibition of HDAC in human HeLa nuclear extract using Boc-Lys(Ac)-AMC as substrate preincubated for 5 mins followed by substrate addition and measured after 30 mins by fluorescence assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4482112
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 264.32 | 2.47 | 2.47 |
| 318.35 | 2.01 | 2.01 |
| 456.50 | 3.58 | 3.58 |
| 510.59 | 4.59 | 4.59 |
| 448.52 | 2.80 | 2.80 |
| 470.96 | 3.94 | 3.94 |
| 468.51 | 3.67 | 3.67 |
| 498.54 | 3.67 | 3.67 |
| 499.01 | 4.72 | 4.72 |
| 502.96 | 4.32 | 4.32 |
| 547.41 | 4.43 | 4.43 |
| 460.53 | 3.09 | 3.09 |
| 482.54 | 3.97 | 3.97 |
| 448.52 | 2.94 | 2.94 |
| 547.41 | 4.43 | 4.43 |
| 594.41 | 4.27 | 4.27 |
| 484.98 | 4.33 | 4.33 |
| 502.96 | 4.32 | 4.32 |
| 469.50 | 3.06 | 3.06 |
| 482.54 | 3.97 | 3.97 |
| 482.54 | 3.34 | 3.34 |
| 432.48 | 2.31 | 2.31 |
| 518.57 | 4.82 | 4.82 |
| 486.50 | 3.81 | 3.81 |
| 536.51 | 4.69 | 4.69 |
| 547.41 | 4.43 | 4.43 |