Basic Information
ID: ALA4482488
Type: Binding
Description: Inhibition of human GOAT expressed in Sf9 cell membranes assessed as reduction in ghrelin octanoylation pre-incubated for 15 mins before substrate addition and measured after 3 hrs using octanoyl-CoA and fluorescent ghrelin peptide by HPLC analysis
Organism: Homo sapiens
Cell type: Sf9
Activity Charts
Bioactivity
Activity Types for Assay ALA4482488
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 456.71 | 7.09 | 7.09 |
| 491.67 | 6.29 | 6.29 |
| 541.74 | 6.74 | 6.74 |
| 505.70 | 6.38 | 6.38 |
| 518.74 | 6.34 | 6.34 |
| 572.71 | 6.88 | 6.88 |