Basic Information
ID: ALA4482518
Type: Binding
Description: Inhibition of HGF-induced IRS1 phosphorylation in human T47D cells assessed as pSer312 IRS1/total-IRS1 ratio level at 20 uM pre-incubated for 4 hrs before stimulation with HGF for 20 mins (Rvb = 100 +/- 0.02%)
Organism: Homo sapiens
Cell type: T47D
Activity Charts
Bioactivity
Activity Types for Assay ALA4482518
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 460.56 | 3.60 | 3.60 |
| 409.62 | 5.80 | 5.80 |
| 493.68 | 5.26 | 5.26 |
| 467.66 | 5.43 | 5.43 |
| 495.71 | 5.91 | 5.91 |
| 481.68 | 5.98 | 5.98 |
| 488.70 | 4.45 | 4.45 |
| 584.73 | 4.63 | 4.63 |
| 469.50 | 1.70 | 1.70 |
| 422.38 | 4.46 | 4.46 |
| 484.05 | 4.93 | 4.93 |
| 389.44 | 4.87 | 4.87 |
| 459.98 | 4.02 | 4.02 |
| 413.36 | 4.51 | 4.51 |
| 334.43 | 3.80 | 3.80 |
| 412.95 | 4.31 | 4.31 |
| 501.53 | 6.25 | 6.25 |
| 472.01 | 3.44 | 3.44 |
| 475.98 | 4.86 | 4.86 |
| 370.46 | 3.63 | 3.63 |
| 422.56 | 2.58 | 2.58 |