Basic Information
ID: ALA4482792
Type: Binding
Description: Inhibition of NAE (unknown origin) using GST-tagged Ubc12 and Flag-tagged Nedd8 measured after 2 hrs by TR-FRET assay
Format: BAO_0000223
Organism: Homo sapiens
Target: NEDD8 activating enzyme(ALA3831283)
Document: ALA4482323
Inhibition of NAE (unknown origin) using GST-tagged Ubc12 and Flag-tagged Nedd8 measured after 2 hrs by TR-FRET assay: 38
Activity Charts
Bioactivity
Activity Types for Assay ALA4482792
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 605.60 | 2.47 | 2.47 |
| 567.62 | 1.46 | 1.46 |
| 555.59 | 1.59 | 1.59 |
| 637.61 | 2.92 | 2.92 |
| 587.61 | 2.04 | 2.04 |
| 606.49 | 2.76 | 2.76 |
| 572.04 | 2.11 | 2.11 |
| 521.60 | 2.48 | 2.48 |
| 573.58 | 1.73 | 1.73 |
| 605.65 | 2.75 | 2.75 |
| 681.64 | 4.25 | 4.25 |
| 537.60 | 1.45 | 1.45 |
| 640.69 | 1.43 | 1.43 |
| 634.48 | 2.35 | 2.35 |
| 573.58 | 1.73 | 1.73 |