Basic Information
ID: ALA4495583
Type: Functional
Description: SARS-CoV-2 3CL-Pro protease inhibition IC50 determined by FRET kind of response from peptide substrate
Organism: Severe acute respiratory syndrome coronavirus 2
Activity Charts
Bioactivity
Activity Types for Assay ALA4495583
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 270.24 | 2.58 | 2.58 |
| 270.24 | 2.58 | 2.58 |
| 302.37 | 3.57 | 3.57 |
| 189.17 | -0.55 | -0.55 |
| 369.37 | 3.52 | 3.52 |
| 300.05 | ||
| 222.27 | 0.66 | 0.66 |
| 255.32 | 2.38 | 2.38 |
| 209.30 | 2.57 | 2.57 |
| 458.38 | 2.23 | 2.23 |
| 274.18 | ||
| 552.68 | 2.72 | 2.72 |
| 209.25 | 2.55 | 2.55 |
| 296.55 | 3.62 | 3.62 |
| 351.86 | 2.69 | 2.69 |
| 318.24 | 1.69 | 1.69 |
| 220.18 | 1.02 | 1.02 |
| 278.22 | 1.15 | 1.15 |
| 154.60 | 2.11 | 2.11 |
| 167.26 | 2.59 | 2.59 |
| 360.32 | 1.76 | 1.76 |
| 299.31 | -1.69 | -1.69 |
| 240.44 | 2.06 | 2.06 |
| 444.40 | 6.99 | 6.99 |
| 182.22 | 3.21 | 3.21 |
| 259.74 | 1.98 | 1.98 |
| 226.35 | 3.30 | 3.30 |
| 342.41 | 0.92 | 0.92 |
| 245.88 | 2.52 | 2.52 |
| 555.52 | 7.13 | 7.13 |
| 178.22 | 0.95 | 0.95 |
| 300.59 | 2.91 | 2.91 |
| 353.20 | 2.18 | 2.18 |
| 188.32 | 2.95 | 2.95 |
| 436.32 | 3.42 | 3.42 |
| 207.25 | 1.81 | 1.81 |
| 245.27 | 0.69 | 0.69 |
| 249.34 | 2.80 | 2.80 |
| 404.82 | ||
| 431.54 | 4.26 | 4.26 |
| 268.27 | -2.71 | -2.71 |
| 257.26 | 0.81 | 0.81 |
| 350.46 | 6.20 | 6.20 |
| 516.58 | 2.55 | 2.55 |
| 160.18 | 1.52 | 1.52 |
| 332.50 | 5.71 | 5.71 |
| 624.59 | -1.02 | -1.02 |
| 302.28 | 1.32 | 1.32 |
| 333.39 | 3.13 | 3.13 |
| 290.26 | 1.92 | 1.92 |
| 336.23 | 2.38 | 2.38 |
| 261.31 | 1.64 | 1.64 |
| 379.38 | 2.26 | 2.26 |
| 261.35 | 3.48 | 3.48 |
| 208.38 | 1.41 | 1.41 |
| 331.46 | 5.32 | 5.32 |
| 257.25 | -1.76 | -1.76 |
| 308.34 | 2.67 | 2.67 |
| 267.36 | 3.13 | 3.13 |
| 381.43 | 2.99 | 2.99 |
| 182.22 | -0.25 | -0.25 |
| 226.23 | -0.05 | -0.05 |
| 293.71 | -1.76 | -1.76 |
| 303.79 | 2.65 | 2.65 |
| 334.37 | 1.76 | 1.76 |
| 374.65 | 2.56 | 2.56 |
| 361.61 | 2.65 | 2.65 |
| 336.74 | ||
| 127.17 | 0.61 | 0.61 |
| 183.16 | -0.18 | -0.18 |
| 253.32 | 1.41 | 1.41 |
| 357.14 | 0.86 | 0.86 |
| 415.49 | 5.25 | 5.25 |
| 199.99 | -0.66 | -0.66 |
| 415.46 | 4.69 | 4.69 |
| 164.30 | 1.30 | 1.30 |
| 284.31 | 3.28 | 3.28 |
| 346.41 | 2.29 | 2.29 |
| 264.42 | 4.23 | 4.23 |
| 302.36 | 1.85 | 1.85 |
| 273.33 | 3.81 | 3.81 |
| 240.30 | 3.46 | 3.46 |
| 316.36 | 2.56 | 2.56 |
| 706.69 | ||
| 750.76 | 0.39 | 0.39 |
| 349.86 | 2.98 | 2.98 |
| 392.18 | ||
| 862.75 | -1.10 | -1.10 |
| 320.25 | 0.89 | 0.89 |
| 317.71 | 1.45 | 1.45 |
| 437.55 | 3.30 | 3.30 |
| 334.40 | 3.26 | 3.26 |
| 380.47 | 3.47 | 3.47 |
| 718.62 | 3.33 | 3.33 |
| 381.35 | 3.56 | 3.56 |
| 668.67 | 0.01 | 0.01 |
| 540.52 | -0.63 | -0.63 |
| 487.80 | 2.91 | 2.91 |
| 464.38 | 0.19 | 0.19 |
| 412.26 | 3.11 | 3.11 |
| 401.47 | 3.80 | 3.80 |
| 348.44 | 1.40 | 1.40 |
| 237.05 | 2.23 | 2.23 |
| 283.33 | 3.70 | 3.70 |
| 223.29 | 1.39 | 1.39 |
| 618.52 | ||
| 680.51 | ||
| 358.26 | 2.85 | 2.85 |