ID: ALA4513085
Type: Toxicity
Description: Cytotoxicity index (CI): selectivity for inhibition of SARS-CoV-2 induced cytotoxicity of VERO-E6 cells versus toxicity against VERO-E6 cells (CC50/IC50)
Format: BAO_0000219
Organism: Chlorocebus sabaeus
Cell type: Vero C1008
Target: ADMET(ALA612558)
Document: ALA4495565
Cytotoxicity index (CI): selectivity for inhibition of SARS-CoV-2 induced cytotoxicity of VERO-E6 cells versus toxicity against VERO-E6 cells (CC50/IC50): 52
Bioactivity
Activity Types for Assay ALA4513085
Selectivity index
Parent Molecular Weight | ALogP | Polar Surface Area |
---|---|---|
391.56 | 6.86 | 6.86 |
440.42 | 0.24 | 0.24 |
350.03 | 5.94 | 5.94 |
348.49 | 6.29 | 6.29 |
369.43 | 2.74 | 2.74 |
475.62 | 4.56 | 4.56 |
432.52 | 7.39 | 7.39 |
280.36 | 1.96 | 1.96 |
355.87 | 5.18 | 5.18 |
504.45 | 5.08 | 5.08 |
299.31 | -1.32 | -1.32 |
352.74 | 5.22 | 5.22 |
360.21 | 4.15 | 4.15 |
356.06 | 5.86 | 5.86 |
454.45 | 0.27 | 0.27 |
477.05 | 5.09 | 5.09 |
269.13 | 2.92 | 2.92 |
320.34 | 2.73 | 2.73 |
410.56 | 4.34 | 4.34 |
314.41 | 4.13 | 4.13 |
532.52 | 6.45 | 6.45 |
235.25 | -0.53 | -0.53 |
355.83 | 3.73 | 3.73 |
209.25 | 2.55 | 2.55 |
582.06 | 8.09 | 8.09 |
475.63 | 3.59 | 3.59 |
282.39 | 4.42 | 4.42 |
400.48 | 1.82 | 1.82 |
332.31 | 3.67 | 3.67 |
243.31 | 4.73 | 4.73 |
616.93 | 9.97 | 9.97 |
466.59 | 4.19 | 4.19 |
500.43 | 8.64 | 8.64 |
510.06 | 6.08 | 6.08 |
497.50 | 1.02 | 1.02 |
281.35 | 1.04 | 1.04 |
562.72 | 5.03 | 5.03 |
663.90 | 4.75 | 4.75 |
503.59 | 5.27 | 5.27 |
1632.29 | ||
265.31 | 0.50 | 0.50 |
355.87 | 5.23 | 5.23 |
386.45 | 4.81 | 4.81 |
262.27 | -0.79 | -0.79 |
622.76 | 7.16 | 7.16 |
472.61 | 5.74 | 5.74 |
413.50 | 5.66 | 5.66 |
387.61 | 5.25 | 5.25 |
567.80 | 4.75 | 4.75 |
485.63 | 4.17 | 4.17 |
333.39 | 4.18 | 4.18 |
152.12 | -0.96 | -0.96 |
314.21 | 3.78 | 3.78 |
426.52 | 4.60 | 4.60 |
327.12 | 3.86 | 3.86 |
380.83 | 4.49 | 4.49 |
568.10 | 3.99 | 3.99 |
356.18 | 3.42 | 3.42 |
441.46 | 3.42 | 3.42 |
413.28 | ||
378.82 | 5.93 | 5.93 |
696.84 | 7.06 | 7.06 |
641.62 | 6.11 | 6.11 |
442.48 | 4.56 | 4.56 |
408.63 | 5.64 | 5.64 |
539.45 | 6.16 | 6.16 |
392.46 | 5.28 | 5.28 |
401.90 | 2.35 | 2.35 |
316.47 | 4.18 | 4.18 |
518.42 | 6.93 | 6.93 |
494.60 | 4.04 | 4.04 |
267.36 | 4.26 | 4.26 |
500.36 | 5.43 | 5.43 |
440.60 | 4.94 | 4.94 |
519.61 | 3.47 | 3.47 |
315.59 | 5.29 | 5.29 |
319.37 | 3.07 | 3.07 |
390.24 | 4.34 | 4.34 |
1214.65 | ||
483.47 | 0.63 | 0.63 |
533.96 | 1.02 | 1.02 |
477.48 | 0.98 | 0.98 |
598.09 | 6.56 | 6.56 |
547.54 | 6.08 | 6.08 |
425.49 | 2.25 | 2.25 |
308.35 | 2.84 | 2.84 |
446.53 | 3.14 | 3.14 |
480.43 | 4.95 | 4.95 |
403.01 | 4.83 | 4.83 |
599.09 | 5.46 | 5.46 |
443.64 | 3.47 | 3.47 |
418.50 | 3.18 | 3.18 |
300.32 | 2.80 | 2.80 |
395.29 | 4.05 | 4.05 |
324.46 | 6.06 | 6.06 |
531.60 | 2.19 | 2.19 |
478.46 | 6.02 | 6.02 |
420.37 | 4.70 | 4.70 |
380.54 | 4.40 | 4.40 |
621.91 | 6.02 | 6.02 |
498.66 | 5.26 | 5.26 |
498.61 | 0.90 | 0.90 |
482.82 | 5.69 | 5.69 |
638.66 | 7.10 | 7.10 |
540.70 | 4.70 | 4.70 |
637.00 | 5.21 | 5.21 |
696.96 | 8.74 | 8.74 |
427.51 | 5.48 | 5.48 |
751.01 | 6.19 | 6.19 |
361.03 | ||
415.50 | 5.88 | 5.88 |
467.49 | 3.50 | 3.50 |
305.17 | 3.88 | 3.88 |
445.44 | 6.71 | 6.71 |
361.21 | 4.01 | 4.01 |
546.71 | 5.02 | 5.02 |
633.70 | 4.75 | 4.75 |
477.52 | 5.47 | 5.47 |
242.30 | 2.84 | 2.84 |
569.64 | 3.95 | 3.95 |
534.66 | 5.73 | 5.73 |
491.35 | 5.38 | 5.38 |
562.60 | 5.00 | 5.00 |
532.37 | 6.53 | 6.53 |
443.86 | 2.86 | 2.86 |
428.49 | 3.77 | 3.77 |
500.48 | 5.73 | 5.73 |
555.64 | 7.94 | 7.94 |
503.49 | 5.75 | 5.75 |
464.31 | 5.68 | 5.68 |
230.35 | 2.40 | 2.40 |
319.37 | 2.61 | 2.61 |
425.92 | 3.86 | 3.86 |
375.46 | 4.57 | 4.57 |
463.56 | 3.95 | 3.95 |
619.72 | 6.22 | 6.22 |
330.39 | 4.14 | 4.14 |
454.91 | 7.35 | 7.35 |
428.54 | 3.49 | 3.49 |
564.57 | 6.03 | 6.03 |
235.24 | 2.54 | 2.54 |
394.86 | 3.40 | 3.40 |
306.41 | 3.79 | 3.79 |
429.55 | 5.65 | 5.65 |
451.55 | 3.70 | 3.70 |
336.42 | 4.98 | 4.98 |
692.86 | 4.27 | 4.27 |