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Cytotoxicity index (CI): selectivity for inhibition of SARS-CoV-2 induced cytotoxicity of VERO-E6 cells versus toxicity against VERO-E6 cells (CC50/IC...

Basic Information

ID: ALA4513085

Type: Toxicity

Description: Cytotoxicity index (CI): selectivity for inhibition of SARS-CoV-2 induced cytotoxicity of VERO-E6 cells versus toxicity against VERO-E6 cells (CC50/IC50)

Format: BAO_0000219

Organism: Chlorocebus sabaeus

Cell type: Vero C1008

Target:  ADMET(ALA612558)

Document:  ALA4495565

Cytotoxicity index (CI): selectivity for inhibition of SARS-CoV-2 induced cytotoxicity of VERO-E6 cells versus toxicity against VERO-E6 cells (CC50/IC50): 52

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
391.566.866.86
440.420.240.24
350.035.945.94
348.496.296.29
369.432.742.74
475.624.564.56
432.527.397.39
280.361.961.96
355.875.185.18
504.455.085.08
299.31-1.32-1.32
352.745.225.22
360.214.154.15
356.065.865.86
454.450.270.27
477.055.095.09
269.132.922.92
320.342.732.73
410.564.344.34
314.414.134.13
532.526.456.45
235.25-0.53-0.53
355.833.733.73
209.252.552.55
582.068.098.09
475.633.593.59
282.394.424.42
400.481.821.82
332.313.673.67
243.314.734.73
616.939.979.97
466.594.194.19
500.438.648.64
510.066.086.08
497.501.021.02
281.351.041.04
562.725.035.03
663.904.754.75
503.595.275.27
1632.29
265.310.500.50
355.875.235.23
386.454.814.81
262.27-0.79-0.79
622.767.167.16
472.615.745.74
413.505.665.66
387.615.255.25
567.804.754.75
485.634.174.17
333.394.184.18
152.12-0.96-0.96
314.213.783.78
426.524.604.60
327.123.863.86
380.834.494.49
568.103.993.99
356.183.423.42
441.463.423.42
413.28
378.825.935.93
696.847.067.06
641.626.116.11
442.484.564.56
408.635.645.64
539.456.166.16
392.465.285.28
401.902.352.35
316.474.184.18
518.426.936.93
494.604.044.04
267.364.264.26
500.365.435.43
440.604.944.94
519.613.473.47
315.595.295.29
319.373.073.07
390.244.344.34
1214.65
483.470.630.63
533.961.021.02
477.480.980.98
598.096.566.56
547.546.086.08
425.492.252.25
308.352.842.84
446.533.143.14
480.434.954.95
403.014.834.83
599.095.465.46
443.643.473.47
418.503.183.18
300.322.802.80
395.294.054.05
324.466.066.06
531.602.192.19
478.466.026.02
420.374.704.70
380.544.404.40
621.916.026.02
498.665.265.26
498.610.900.90
482.825.695.69
638.667.107.10
540.704.704.70
637.005.215.21
696.968.748.74
427.515.485.48
751.016.196.19
361.03
415.505.885.88
467.493.503.50
305.173.883.88
445.446.716.71
361.214.014.01
546.715.025.02
633.704.754.75
477.525.475.47
242.302.842.84
569.643.953.95
534.665.735.73
491.355.385.38
562.605.005.00
532.376.536.53
443.862.862.86
428.493.773.77
500.485.735.73
555.647.947.94
503.495.755.75
464.315.685.68
230.352.402.40
319.372.612.61
425.923.863.86
375.464.574.57
463.563.953.95
619.726.226.22
330.394.144.14
454.917.357.35
428.543.493.49
564.576.036.03
235.242.542.54
394.863.403.40
306.413.793.79
429.555.655.65
451.553.703.70
336.424.984.98
692.864.274.27