Basic Information
ID: ALA4603183
Type: Binding
Description: Aggregation-based inhibition of human recombinant AKR1B1 assessed as D,L-glyceraldehyde reduction incubated in sodium phosphate buffer at pH 6.2 in presence of NADPH and 0.05% Triton X-100 by detergent-addition assay
Format: BAO_0000357
Organism: Homo sapiens
Target: Aldose reductase(ALA1900)
Document: ALA4602613
Aggregation-based inhibition of human recombinant AKR1B1 assessed as D,L-glyceraldehyde reduction incubated in sodium phosphate buffer at pH 6.2 in presence of NADPH and 0.05% Triton X-100 by detergent-addition assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4603183
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 216.24 | 1.06 | 1.06 |
| 218.26 | 1.22 | 1.22 |
| 268.27 | 1.48 | 1.48 |
| 304.39 | 2.32 | 2.32 |
| 348.36 | -0.80 | -0.80 |
| 236.23 | 0.46 | 0.46 |