Basic Information
ID: ALA4603689
Type: Binding
Description: Agonist activity at human TLR8 expressed in HEK-Blue cells assessed as induction of NFkappaB activation by measuring increase in SEAP level by SEAP reporter gene-based UV-vis absorbance method
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4603689
EC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 314.39 | 2.47 | 2.47 |
| 346.86 | 3.93 | 3.93 |
| 342.44 | 3.29 | 3.29 |
| 321.43 | 4.04 | 4.04 |
| 326.44 | 4.17 | 4.17 |
| 348.83 | 3.13 | 3.13 |
| 337.43 | 3.15 | 3.15 |
| 323.40 | 3.23 | 3.23 |
| 330.86 | 4.82 | 4.82 |
| 339.40 | 2.35 | 2.35 |
| 332.84 | 4.01 | 4.01 |
| 312.42 | 3.87 | 3.87 |