Basic Information
ID: ALA4603781
Type: Binding
Description: Irreversible inhibition of binding of N-(2-((6-((but-3-yn-1-yloxy) (phenyl)methyl)-2-(6-(difluoromethyl)-1H-indazol-3-yl)-1H-indol-4-yl)oxy)ethyl)acrylamide to recombinant ITK (unknown origin) at 50 uM pretreated with compound prior to probe addition by fluorescence scan analysis
Format: BAO_0000357
Organism: Homo sapiens
Target: Tyrosine-protein kinase ITK/TSK(ALA2959)
Document: ALA4602634
Irreversible inhibition of binding of N-(2-((6-((but-3-yn-1-yloxy) (phenyl)methyl)-2-(6-(difluoromethyl)-1H-indazol-3-yl)-1H-indol-4-yl)oxy)ethyl)acrylamide to recombinant ITK (unknown origin) at 50 uM pretreated with compound prior to probe addition by fluorescence scan analysis: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4603781
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 623.85 | 5.69 | 5.69 |
| 543.68 | 5.41 | 5.41 |
| 502.58 | 5.37 | 5.37 |
| 486.52 | 5.92 | 5.92 |