Basic Information
ID: ALA4603821
Type: Binding
Description: Inhibition of ITK in anti-CD3/CD28 beads-stimulated human Jurkat cells assessed as reduction in Plcgamma1 phosphorylation at 0.3 uM incubated for 2 hrs followed by stimulation with anti-CD3/CD28 beads by Western blot analysis relative to control
Organism: Homo sapiens
Cell type: Jurkat
Activity Charts
Bioactivity
Activity Types for Assay ALA4603821
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 502.58 | 5.37 | 5.37 |
| 486.52 | 5.92 | 5.92 |