Basic Information
ID: ALA4603822
Type: Binding
Description: Inhibition of ITK in anti-CD3/CD28 beads-stimulated human Jurkat cells assessed as reduction in Plcgamma1 phosphorylation incubated for 2 hrs followed by stimulation with anti-CD3/CD28 beads by Western blot analysis
Format: BAO_0000219
Organism: Homo sapiens
Cell type: Jurkat
Target: Tyrosine-protein kinase ITK/TSK(ALA2959)
Document: ALA4602634
Inhibition of ITK in anti-CD3/CD28 beads-stimulated human Jurkat cells assessed as reduction in Plcgamma1 phosphorylation incubated for 2 hrs followed by stimulation with anti-CD3/CD28 beads by Western blot analysis: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4603822
EC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 543.68 | 5.41 | 5.41 |
| 502.58 | 5.37 | 5.37 |
| 486.52 | 5.92 | 5.92 |