Assay Report Card

Basic Information

ID: ALA4604224

Type: Binding

Description: Protac activity at CRBN/CDK2 in AR-negative human PC3 cells assessed as induction of CDK2 protein degradation at 50 nM after 12 hrs by Western blot analysis

Organism: Homo sapiens

Cell type: PC-3

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
871.963.293.29
844.892.482.48
843.912.512.51
815.851.731.73
876.890.950.95