Protac activity at CRBN/CDK9 in AR-negative human PC3 cells assessed as induction of CDK9 protein degradation at 50 nM after 12 hrs by Western blot an...

Basic Information

ID: ALA4604225

Type: Binding

Description: Protac activity at CRBN/CDK9 in AR-negative human PC3 cells assessed as induction of CDK9 protein degradation at 50 nM after 12 hrs by Western blot analysis

Format: BAO_0000219

Organism: Homo sapiens

Cell type: PC-3

Target: Protein cereblon/CDK9(ALA4523697)

Document: ALA4602651

Protac activity at CRBN/CDK9 in AR-negative human PC3 cells assessed as induction of CDK9 protein degradation at 50 nM after 12 hrs by Western blot analysis: 1

Associated Items: Associated Bioactivities Associated Compounds

Activity Charts

Bioactivity

Activity Types for Assay ALA4604225

Activity

Total(5)

Parent Molecular Weight	ALogP	Polar Surface Area
871.96	3.29	3.29
844.89	2.48	2.48
843.91	2.51	2.51
815.85	1.73	1.73
876.89	0.95	0.95

Parent Molecular Weight

ALogP

Polar Surface Area

871.96

3.29

844.89

2.48

843.91

2.51

815.85

1.73

876.89

0.95

Protac activity at CRBN/CDK9 in AR-negative human PC3 cells assessed as induction of CDK9 protein degradation at 50 nM after 12 hrs by Western blot an...

Basic Information

Activity Charts

Compound Summary