Assay Report Card

Basic Information

ID: ALA4604235

Type: Binding

Description: Protac activity at CRBN/CDK2/CDK9 in AR-negative human PC3 cells assessed as CDK2 degradation at 250 nM preincubated with proteasome inhibitor MG132 for 2 hrs and measured after 8 hrs by Western blot analysis

Organism: Homo sapiens

Cell type: PC-3

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
815.851.731.73