Inhibition of CYP2D6 in human liver microsomes using dextromethorphan as substrate incubated for 12 min in presence of NADPH by LC-MS/MS analysis

Basic Information

ID: ALA4604696

Type: ADME

Description: Inhibition of CYP2D6 in human liver microsomes using dextromethorphan as substrate incubated for 12 min in presence of NADPH by LC-MS/MS analysis

Format: BAO_0000251

Organism: Homo sapiens

Tissue: Liver

Subcellular Fraction: Microsomes

Target:  Cytochrome P450 2D6(ALA289)

Document:  ALA4602676

Inhibition of CYP2D6 in human liver microsomes using dextromethorphan as substrate incubated for 12 min in presence of NADPH by LC-MS/MS analysis: 1

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
226.711.071.07
261.151.861.86
240.731.601.60
261.151.861.86
261.151.861.86
275.182.252.25
244.701.351.35
226.711.211.21
226.711.211.21
261.151.861.86
261.151.861.86
261.151.721.72
261.151.861.86