ID: ALA4604696
Type: ADME
Description: Inhibition of CYP2D6 in human liver microsomes using dextromethorphan as substrate incubated for 12 min in presence of NADPH by LC-MS/MS analysis
Format: BAO_0000251
Organism: Homo sapiens
Tissue: Liver
Subcellular Fraction: Microsomes
Target: Cytochrome P450 2D6(ALA289)
Document: ALA4602676
Inhibition of CYP2D6 in human liver microsomes using dextromethorphan as substrate incubated for 12 min in presence of NADPH by LC-MS/MS analysis: 1
Bioactivity
Activity Types for Assay ALA4604696
IC50
Parent Molecular Weight | ALogP | Polar Surface Area |
---|---|---|
226.71 | 1.07 | 1.07 |
261.15 | 1.86 | 1.86 |
240.73 | 1.60 | 1.60 |
261.15 | 1.86 | 1.86 |
261.15 | 1.86 | 1.86 |
275.18 | 2.25 | 2.25 |
244.70 | 1.35 | 1.35 |
226.71 | 1.21 | 1.21 |
226.71 | 1.21 | 1.21 |
261.15 | 1.86 | 1.86 |
261.15 | 1.86 | 1.86 |
261.15 | 1.72 | 1.72 |
261.15 | 1.86 | 1.86 |