Assay Report Card

Basic Information

ID: ALA4605235

Type: Binding

Description: Antagonist activity at muscarinic M3 receptor (unknown origin) expressed in HEK293 cells coexpressing EA tagged beta-arrestin2 assessed as inhibition of carbachol-induced beta-arrestin2 recruitment preincubated for 30 mins followed by carbachol addition and measured after 90 mins by PathHunter assay

Organism: Homo sapiens

Cell type: HEK293

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
426.563.963.96
452.895.075.07
380.824.834.83
472.432.352.35
392.834.934.93
362.834.694.69
434.904.934.93
374.844.794.79