Basic Information
ID: ALA4605237
Type: Binding
Description: Antagonist activity at muscarinic M3 receptor (unknown origin) expressed in HEK293 cells coexpressing EA tagged beta-arrestin2 assessed as inhibition of carbachol-induced beta-arrestin2 recruitment preincubated for 30 mins followed by carbachol addition and measured after 90 mins by PathHunter assay relative to quinpirole
Organism: Homo sapiens
Cell type: HEK293
Activity Charts
Bioactivity
Activity Types for Assay ALA4605237
Emax
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 426.56 | 3.96 | 3.96 |
| 452.89 | 5.07 | 5.07 |
| 380.82 | 4.83 | 4.83 |
| 472.43 | 2.35 | 2.35 |
| 392.83 | 4.93 | 4.93 |
| 362.83 | 4.69 | 4.69 |
| 434.90 | 4.93 | 4.93 |
| 374.84 | 4.79 | 4.79 |