Basic Information
ID: ALA4605248
Type: Functional
Description: Ratio of EC50 for darifenacin to EC50 for test compound for antagonist activity at human muscarinic M3 receptor expressed in HEK293 assessed as inhibition of carbachol-induced IP1 accumulation preincubated for 30 mins followed by carbachol addition and measured after 90 mins by TR-HTRF assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4605248
Ratio EC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 452.89 | 5.07 | 5.07 |
| 380.82 | 4.83 | 4.83 |
| 392.83 | 4.93 | 4.93 |
| 362.83 | 4.69 | 4.69 |
| 434.90 | 4.93 | 4.93 |
| 374.84 | 4.79 | 4.79 |