Basic Information
ID: ALA4605381
Type: Binding
Description: Displacement of 4-(2-((1E,3E)-5-((E)-3,3-Dimethyl-1-(6-oxo-6-((2-(3-(1-(4-(1-(2-oxo-2-(11-oxo-10,11-dihydro-5H-dibenzo[b,e][1,4]diazepin-5-yl)ethyl)piperidin-4-yl)butyl)-1H-imidazol-4-yl)propanamido)ethyl)-amino)hexyl)-5-sulfoindolin-2-ylidene)penta-1,3-dien-1-yl)-3,3-dimethyl-3H-indol-1-ium-1-yl)butane-1-sulfonateHydrotrifluoroacetate fluorescent tracer from human muscarinic M2 receptor expressed in CHO-K9 cells measured after 60 mins by Hoechst H33342 dye based confocal plate reader assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4605381
Ki
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 206.29 | 0.71 | 0.71 |
| 708.54 | 4.07 | 4.07 |
| 281.42 | 3.22 | 3.22 |
| 289.38 | 1.93 | 1.93 |
| 318.39 | 1.06 | 1.06 |
| 437.95 | 1.89 | 1.89 |
| 1358.66 |