Basic Information
ID: ALA4605391
Type: ADME
Description: Inhibition of C-terminal His6-tagged human DHODH expressed in Escherichia coli BL21(DE3) cells using L-DHO as substrate by DCIP dye based assay
Format: BAO_0000219
Organism: Homo sapiens
Target: Dihydroorotate dehydrogenase(ALA1966)
Document: ALA4602703
Inhibition of C-terminal His6-tagged human DHODH expressed in Escherichia coli BL21(DE3) cells using L-DHO as substrate by DCIP dye based assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4605391
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 270.21 | 3.00 | 3.00 |
| 301.39 | 3.80 | 3.80 |
| 415.34 | 5.95 | 5.95 |
| 339.36 | 4.43 | 4.43 |
| 255.32 | 2.20 | 2.20 |
| 361.35 | 2.02 | 2.02 |
| 323.32 | 3.22 | 3.22 |
| 309.29 | 2.91 | 2.91 |
| 326.32 | 3.81 | 3.81 |
| 325.33 | 3.47 | 3.47 |
| 351.37 | 3.92 | 3.92 |
| 345.75 | 4.76 | 4.76 |
| 269.30 | 2.36 | 2.36 |
| 337.35 | 3.48 | 3.48 |
| 339.32 | 3.73 | 3.73 |
| 325.33 | 3.47 | 3.47 |
| 339.32 | 2.40 | 2.40 |
| 323.32 | 3.17 | 3.17 |
| 310.32 | 4.31 | 4.31 |
| 355.34 | 3.56 | 3.56 |
| 340.32 | 3.96 | 3.96 |
| 341.31 | 3.12 | 3.12 |
| 324.31 | 2.61 | 2.61 |
| 358.31 | 4.10 | 4.10 |
| 359.30 | 3.42 | 3.42 |
| 367.37 | 3.24 | 3.24 |
| 337.35 | 3.53 | 3.53 |
| 326.32 | 3.81 | 3.81 |
| 337.35 | 3.48 | 3.48 |
| 324.35 | 3.99 | 3.99 |
| 366.39 | 2.81 | 2.81 |
| 325.33 | 3.39 | 3.39 |
| 317.39 | 3.42 | 3.42 |
| 337.35 | 3.61 | 3.61 |
| 308.30 | 3.92 | 3.92 |
| 329.29 | 4.25 | 4.25 |
| 353.39 | 4.12 | 4.12 |
| 352.40 | 4.77 | 4.77 |
| 373.33 | 3.86 | 3.86 |
| 339.36 | 3.86 | 3.86 |
| 352.36 | 3.83 | 3.83 |
| 325.33 | 4.42 | 4.42 |
| 351.33 | 3.17 | 3.17 |
| 325.33 | 3.34 | 3.34 |
| 380.41 | 3.15 | 3.15 |
| 365.28 | 3.62 | 3.62 |
| 322.33 | 3.82 | 3.82 |
| 337.35 | 3.53 | 3.53 |
| 341.33 | 4.12 | 4.12 |
| 352.36 | 2.37 | 2.37 |
| 339.36 | 3.86 | 3.86 |
| 356.78 | 4.48 | 4.48 |
| 347.28 | 4.39 | 4.39 |
| 339.36 | 3.78 | 3.78 |
| 338.33 | 2.03 | 2.03 |
| 311.30 | 4.11 | 4.11 |
| 337.35 | 3.56 | 3.56 |
| 351.37 | 3.92 | 3.92 |
| 391.32 | 4.15 | 4.15 |
| 391.32 | 4.24 | 4.24 |
| 299.41 | 4.52 | 4.52 |
| 338.37 | 4.38 | 4.38 |
| 353.34 | 3.06 | 3.06 |
| 301.39 | 3.80 | 3.80 |
| 337.35 | 3.56 | 3.56 |
| 297.28 | 3.94 | 3.94 |
| 324.31 | 2.61 | 2.61 |
| 323.32 | 3.22 | 3.22 |
| 340.30 | 3.45 | 3.45 |
| 351.37 | 3.95 | 3.95 |
| 287.36 | 3.41 | 3.41 |
| 339.32 | 2.71 | 2.71 |