Selectivity ratio of EC50 for inhibition of yeast DHODH expressed in Plasmodium falciparum D10 in presence of 10 uM proguanil to EC50 for antimalarial...

Basic Information

ID: ALA4605411

Type: Unassigned

Description: Selectivity ratio of EC50 for inhibition of yeast DHODH expressed in Plasmodium falciparum D10 in presence of 10 uM proguanil to EC50 for antimalarial activity against multidrug-resistant Plasmodium falciparum Dd2

Format: BAO_0000019

Target:  Unchecked(ALA612545)

Document:  ALA4602703

Selectivity ratio of EC50 for inhibition of yeast DHODH expressed in Plasmodium falciparum D10 in presence of 10 uM proguanil to EC50 for antimalarial activity against multidrug-resistant Plasmodium falciparum Dd2: 1

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
415.345.955.95
323.323.223.22