Inhibition of CYP3A4/5 in human liver microsomes using midazolam as substrate measured for 10 to 30 mins in presence of NADPH regenerating system by U...

Basic Information

ID: ALA4605514

Type: ADME

Description: Inhibition of CYP3A4/5 in human liver microsomes using midazolam as substrate measured for 10 to 30 mins in presence of NADPH regenerating system by UPLC-MS analysis

Format: BAO_0000251

Organism: Homo sapiens

Tissue: Liver

Subcellular Fraction: Microsomes

Target: Cytochrome P450 3A4/3A5(ALA2111472)

Document: ALA4602703

Inhibition of CYP3A4/5 in human liver microsomes using midazolam as substrate measured for 10 to 30 mins in presence of NADPH regenerating system by UPLC-MS analysis: 1

Associated Items: Associated Bioactivities Associated Compounds

Activity Charts

Bioactivity

Activity Types for Assay ALA4605514

IC50

Total(1)

Parent Molecular Weight	ALogP	Polar Surface Area
323.32	3.22	3.22

Parent Molecular Weight

ALogP

Polar Surface Area

323.32

3.22

Inhibition of CYP3A4/5 in human liver microsomes using midazolam as substrate measured for 10 to 30 mins in presence of NADPH regenerating system by U...

Basic Information

Activity Charts

Compound Summary