Basic Information
ID: ALA4605648
Type: ADME
Description: Inhibition of human recombinant CYP3A4 expressed in insect cell microsomes in presence of NADPH by fluorescence assay
Format: BAO_0000251
Organism: Homo sapiens
Subcellular Fraction: Microsomes
Target: Cytochrome P450 3A4(ALA340)
Document: ALA4602709
Inhibition of human recombinant CYP3A4 expressed in insect cell microsomes in presence of NADPH by fluorescence assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4605648
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 529.53 | 6.36 | 6.36 |
| 532.57 | 4.46 | 4.46 |
| 534.66 | 3.68 | 3.68 |
| 534.02 | 5.56 | 5.56 |
| 548.69 | 4.33 | 4.33 |
| 507.99 | 4.58 | 4.58 |
| 524.03 | 4.12 | 4.12 |
| 529.04 | 3.45 | 3.45 |