Basic Information
ID: ALA4605863
Type: Functional
Description: In vivo inhibition of KIF5B/RET transfected in rat RIE cells xenografted in Harlan Foxn1 nude mouse assessed as reduction in RET phosphorylation at 30 mg/kg, po administered bid for 8 days and measured on day 8 after 5 hrs of dosing by Western blot analysis
Organism: Mus musculus
Activity Charts
Bioactivity
Activity Types for Assay ALA4605863
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 579.75 | 5.32 | 5.32 |