Basic Information
ID: ALA4606047
Type: Binding
Description: Selectivity index, ratio of IC50 for human GST-tagged VCPIP CD (25 to 561 residues) expressed in Escherichia coli assessed as cleavage of Ubiquitin-Rhodamine110-glycine to Ubiquitin and Rhodamine110-glycine using Ubiquitin-Rhodamine110-glycine as substrate by fluorescence based analysis to IC50 for inhibition of recombinant full length USP7 (unknown origin) using ubiquintin-rhodamine as substrate preincubated for 30 mins followed by substrate addition measured after 1 hr by fluorescence-based Envision plate reader assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4606047
Ratio IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 524.09 | 5.44 | 5.44 |