Basic Information
ID: ALA4606093
Type: Binding
Description: Reversal of Pgp-mediated DOX resistance in human SW620/AD300 cells assessed as potentiation of DOX-induced cytotoxicity by measuring DOX IC50 at 1 uM incubated for 48 hrs by SRB assay (Rvb = 33.39 +/- 7.08 uM)
Organism: Homo sapiens
Cell type: SW620/AD300
Activity Charts
Bioactivity
Activity Types for Assay ALA4606093
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 454.61 | 5.09 | 5.09 |
| 453.54 | 4.86 | 4.86 |
| 864.52 | 8.42 | 8.42 |
| 626.76 | 7.51 | 7.51 |
| 586.69 | 6.73 | 6.73 |
| 626.76 | 7.30 | 7.30 |
| 439.52 | 4.62 | 4.62 |
| 626.76 | 7.51 | 7.51 |
| 586.69 | 6.81 | 6.81 |
| 548.66 | 6.92 | 6.92 |
| 738.63 | 7.81 | 7.81 |
| 616.75 | 7.21 | 7.21 |
| 644.82 | 6.48 | 6.48 |
| 628.73 | 6.91 | 6.91 |
| 548.68 | 7.39 | 7.39 |
| 626.76 | 7.51 | 7.51 |
| 480.57 | 4.76 | 4.76 |
| 451.53 | 4.68 | 4.68 |
| 465.55 | 4.87 | 4.87 |
| 575.71 | 6.14 | 6.14 |
| 612.73 | 7.21 | 7.21 |
| 542.63 | 4.91 | 4.91 |
| 691.63 | 7.97 | 7.97 |
| 572.71 | 6.51 | 6.51 |
| 647.18 | 7.86 | 7.86 |
| 493.56 | 5.55 | 5.55 |
| 612.73 | 7.21 | 7.21 |
| 542.64 | 6.86 | 6.86 |
| 644.73 | 6.62 | 6.62 |
| 630.72 | 7.34 | 7.34 |
| 612.73 | 7.21 | 7.21 |
| 612.73 | 7.21 | 7.21 |
| 637.74 | 7.08 | 7.08 |