Assay Report Card

Basic Information

ID: ALA4606101

Type: Binding

Description: Reversal of ABCG2-mediated mitoxantrone resistance in human NCI-H460/MX20 cells assessed as potentiation of mitoxantrone-induced cytotoxicity by measuring change in mitoxantrone IC50 at 5 uM incubated for 48 hrs by SRB assay relative to mitoxantrone IC50

Organism: Homo sapiens

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
647.187.867.86