Basic Information
ID: ALA4606150
Type: Binding
Description: Inhibition of human recombinant HDAC1 pre-incubated for 30 mins before Ac-Leu- Gly-Lys(Ac)-AMC substrate addition and measured after 90 mins by fluorescence based assay
Format: BAO_0000357
Organism: Homo sapiens
Target: Histone deacetylase 1(ALA325)
Document: ALA4602725
Inhibition of human recombinant HDAC1 pre-incubated for 30 mins before Ac-Leu- Gly-Lys(Ac)-AMC substrate addition and measured after 90 mins by fluorescence based assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4606150
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 278.35 | 2.96 | 2.96 |
| 270.29 | 1.99 | 1.99 |
| 312.37 | 3.18 | 3.18 |
| 298.34 | 2.72 | 2.72 |
| 457.53 | 4.88 | 4.88 |
| 342.37 | 3.40 | 3.40 |
| 363.42 | 3.74 | 3.74 |
| 463.56 | 5.18 | 5.18 |
| 390.44 | 3.65 | 3.65 |
| 418.50 | 4.26 | 4.26 |
| 313.36 | 2.58 | 2.58 |
| 358.83 | 3.91 | 3.91 |
| 398.46 | 3.66 | 3.66 |
| 499.59 | 6.17 | 6.17 |
| 338.41 | 3.65 | 3.65 |
| 507.59 | 5.90 | 5.90 |
| 447.33 | 4.42 | 4.42 |
| 419.27 | 3.26 | 3.26 |
| 346.39 | 3.58 | 3.58 |
| 469.34 | 4.41 | 4.41 |
| 434.50 | 4.04 | 4.04 |
| 367.45 | 3.32 | 3.32 |
| 346.81 | 3.84 | 3.84 |
| 326.40 | 3.21 | 3.21 |
| 340.38 | 2.49 | 2.49 |
| 339.40 | 2.07 | 2.07 |
| 404.47 | 4.04 | 4.04 |
| 406.44 | 2.88 | 2.88 |
| 390.44 | 3.65 | 3.65 |
| 415.49 | 4.51 | 4.51 |
| 444.49 | 4.62 | 4.62 |
| 401.47 | 4.32 | 4.32 |
| 382.42 | 3.37 | 3.37 |
| 499.59 | 6.17 | 6.17 |
| 355.39 | 2.07 | 2.07 |
| 390.44 | 3.65 | 3.65 |
| 385.38 | 2.40 | 2.40 |
| 325.37 | 2.65 | 2.65 |
| 437.52 | 4.39 | 4.39 |
| 387.48 | 4.90 | 4.90 |
| 312.37 | 2.93 | 2.93 |
| 346.81 | 3.84 | 3.84 |
| 388.47 | 4.80 | 4.80 |
| 326.40 | 3.50 | 3.50 |
| 486.57 | 4.85 | 4.85 |
| 324.38 | 3.26 | 3.26 |
| 390.44 | 3.65 | 3.65 |
| 407.50 | 4.38 | 4.38 |
| 435.44 | 3.55 | 3.55 |
| 409.27 | 3.80 | 3.80 |
| 400.48 | 4.92 | 4.92 |
| 501.58 | 5.28 | 5.28 |
| 457.53 | 4.88 | 4.88 |
| 296.33 | 2.48 | 2.48 |
| 459.55 | 4.90 | 4.90 |
| 374.44 | 4.41 | 4.41 |
| 404.47 | 3.95 | 3.95 |
| 403.28 | 4.02 | 4.02 |
| 417.30 | 4.41 | 4.41 |
| 418.47 | 5.06 | 5.06 |
| 439.52 | 5.40 | 5.40 |
| 410.37 | 4.41 | 4.41 |