Potency index, ratio of IC50 for AR-42 to IC50 for test compound for inhibition of human recombinant HDAC1 pre-incubated for 30 mins before Ac-Leu- Gl...

Basic Information

ID: ALA4606159

Type: Binding

Description: Potency index, ratio of IC50 for AR-42 to IC50 for test compound for inhibition of human recombinant HDAC1 pre-incubated for 30 mins before Ac-Leu- Gly-Lys(Ac)-AMC substrate addition and measured after 90 mins by fluorescence based assay

Format: BAO_0000357

Organism: Homo sapiens

Target:  Histone deacetylase 1(ALA325)

Document:  ALA4602725

Potency index, ratio of IC50 for AR-42 to IC50 for test compound for inhibition of human recombinant HDAC1 pre-incubated for 30 mins before Ac-Leu- Gly-Lys(Ac)-AMC substrate addition and measured after 90 mins by fluorescence based assay: 1

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
390.443.653.65