Potency index, ratio of IC50 for AR-42 to IC50 for test compound for inhibition of HDAC1 in human MM96L cells assessed as activation of histone H4 ace...

Basic Information

ID: ALA4606194

Type: Binding

Description: Potency index, ratio of IC50 for AR-42 to IC50 for test compound for inhibition of HDAC1 in human MM96L cells assessed as activation of histone H4 acetylation at Lys5, Lys8, Lys12 and Lys16 residues by Western blot analysis

Format: BAO_0000219

Organism: Homo sapiens

Cell type: MM96L

Target:  Histone deacetylase 1(ALA325)

Document:  ALA4602725

Potency index, ratio of IC50 for AR-42 to IC50 for test compound for inhibition of HDAC1 in human MM96L cells assessed as activation of histone H4 acetylation at Lys5, Lys8, Lys12 and Lys16 residues by Western blot analysis: 1

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
419.273.263.26
390.443.653.65