Basic Information
ID: ALA4606498
Type: ADME
Description: Half life in human liver microsomes at 10 uM preincubated for 10 mins followed by NADPH addition by LC-MS/MS analysis
Organism: Homo sapiens
Tissue: Liver
Subcellular Fraction: Microsome
Activity Charts
Bioactivity
Activity Types for Assay ALA4606498
t1/2
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 317.78 | 3.61 | 3.61 |
| 297.36 | 3.26 | 3.26 |
| 351.33 | 3.97 | 3.97 |
| 394.36 | 3.09 | 3.09 |
| 332.75 | 1.95 | 1.95 |
| 332.75 | 1.95 | 1.95 |
| 331.76 | 2.55 | 2.55 |
| 415.33 | 2.78 | 2.78 |
| 408.38 | 3.74 | 3.74 |
| 350.30 | 3.34 | 3.34 |
| 394.36 | 3.09 | 3.09 |
| 307.32 | 2.19 | 2.19 |
| 336.28 | 2.95 | 2.95 |
| 365.32 | 2.92 | 2.92 |
| 408.38 | 3.74 | 3.74 |
| 394.36 | 3.09 | 3.09 |
| 366.30 | 2.31 | 2.31 |
| 352.32 | 3.37 | 3.37 |
| 334.74 | 2.92 | 2.92 |
| 316.75 | 2.97 | 2.97 |
| 371.35 | 3.22 | 3.22 |
| 393.37 | 3.06 | 3.06 |
| 318.77 | 3.00 | 3.00 |
| 364.33 | 3.73 | 3.73 |
| 366.30 | 2.31 | 2.31 |
| 430.34 | 3.34 | 3.34 |
| 293.29 | 1.80 | 1.80 |
| 367.31 | 3.89 | 3.89 |
| 379.35 | 2.67 | 2.67 |
| 316.30 | 1.97 | 1.97 |
| 408.38 | 3.74 | 3.74 |
| 309.33 | 2.22 | 2.22 |
| 322.33 | 1.77 | 1.77 |
| 407.40 | 3.32 | 3.32 |
| 324.32 | 2.75 | 2.75 |
| 379.35 | 2.54 | 2.54 |
| 302.73 | 2.58 | 2.58 |
| 395.80 | 2.49 | 2.49 |
| 352.28 | 2.19 | 2.19 |
| 378.36 | 4.12 | 4.12 |
| 314.31 | 1.00 | 1.00 |
| 380.33 | 2.97 | 2.97 |
| 429.35 | 2.86 | 2.86 |
| 408.38 | 3.34 | 3.34 |
| 380.33 | 2.70 | 2.70 |
| 380.33 | 2.97 | 2.97 |
| 307.32 | 1.88 | 1.88 |
| 362.34 | 3.05 | 3.05 |
| 316.75 | 2.66 | 2.66 |
| 415.33 | 2.78 | 2.78 |
| 325.31 | 2.14 | 2.14 |
| 323.32 | 1.16 | 1.16 |
| 379.35 | 2.67 | 2.67 |
| 350.30 | 3.02 | 3.02 |
| 421.43 | 3.66 | 3.66 |
| 379.35 | 2.54 | 2.54 |
| 407.40 | 3.32 | 3.32 |
| 368.29 | 3.29 | 3.29 |
| 436.39 | 3.52 | 3.52 |
| 333.75 | 3.53 | 3.53 |
| 408.38 | 3.34 | 3.34 |
| 394.36 | 3.09 | 3.09 |
| 380.79 | 4.00 | 4.00 |
| 394.36 | 3.09 | 3.09 |
| 386.37 | 1.71 | 1.71 |
| 300.32 | 2.06 | 2.06 |
| 414.34 | 4.37 | 4.37 |
| 366.30 | 2.58 | 2.58 |
| 323.32 | 1.16 | 1.16 |