Basic Information
ID: ALA4610360
Type: Binding
Description: Inhibition of HIV-1 integrase assessed as inhibition of interaction of HIV-1 IN with LEDGF/p75 (unknown origin) at 10 uM preincubated with enzyme for 30 mins followed by further incubation with LEDGF/p75 for 1 hr by Alphascreen assay relative to control
Organism: Human immunodeficiency virus 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4610360
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 201.27 | 3.64 | 3.64 |
| 353.85 | 5.83 | 5.83 |
| 175.19 | 2.35 | 2.35 |
| 145.16 | 2.34 | 2.34 |
| 214.27 | 2.89 | 2.89 |
| 205.21 | 2.36 | 2.36 |
| 258.32 | 3.12 | 3.12 |
| 179.61 | 3.00 | 3.00 |
| 317.16 | 4.44 | 4.44 |
| 286.37 | 4.07 | 4.07 |
| 163.15 | 2.48 | 2.48 |
| 270.33 | 3.78 | 3.78 |
| 345.38 | 2.62 | 2.62 |
| 189.17 | 2.07 | 2.07 |
| 260.77 | 4.71 | 4.71 |
| 256.35 | 4.06 | 4.06 |
| 230.31 | 3.36 | 3.36 |
| 190.16 | 2.25 | 2.25 |
| 264.33 | 3.61 | 3.61 |
| 244.29 | 3.08 | 3.08 |
| 234.73 | 4.00 | 4.00 |
| 256.39 | 4.65 | 4.65 |
| 245.28 | 3.26 | 3.26 |
| 244.31 | 4.19 | 4.19 |
| 346.36 | 2.80 | 2.80 |
| 282.43 | 5.35 | 5.35 |
| 245.28 | 3.26 | 3.26 |
| 202.23 | 3.02 | 3.02 |
| 260.34 | 3.37 | 3.37 |
| 218.27 | 3.49 | 3.49 |
| 278.31 | 3.33 | 3.33 |
| 244.29 | 2.90 | 2.90 |
| 252.29 | 3.74 | 3.74 |
| 190.16 | 2.25 | 2.25 |
| 294.35 | 3.62 | 3.62 |
| 343.18 | 4.03 | 4.03 |
| 359.22 | 4.32 | 4.32 |
| 301.37 | 2.89 | 2.89 |