Basic Information
ID: ALA4610602
Type: ADME
Description: Substrate activity at P-gp in MDCK2-MDR1 cells at 10 uM incubated for 60 mins in presence or absence of 2 uM P-gp inhibitor elacridar by LC-MS/MS analysis
Format: BAO_0000219
Organism: Canis lupus familiaris
Cell type: MDCK-MDR1
Target: Unchecked(ALA612545)
Document: ALA4609995
Substrate activity at P-gp in MDCK2-MDR1 cells at 10 uM incubated for 60 mins in presence or absence of 2 uM P-gp inhibitor elacridar by LC-MS/MS analysis: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4610602
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 193.17 | -1.63 | -1.63 |
| 270.25 | -0.56 | -0.56 |
| 283.29 | -0.04 | -0.04 |
| 287.25 | 0.18 | 0.18 |
| 299.29 | 0.05 | 0.05 |
| 269.26 | 0.04 | 0.04 |
| 252.27 | 1.89 | 1.89 |
| 367.37 | 0.25 | 0.25 |
| 241.25 | 0.68 | 0.68 |
| 348.34 | -1.31 | -1.31 |
| 300.28 | -1.26 | -1.26 |
| 312.33 | 0.11 | 0.11 |
| 255.24 | 0.03 | 0.03 |
| 294.27 | -0.09 | -0.09 |
| 285.26 | -0.25 | -0.25 |