Basic Information
ID: ALA4610690
Type: Functional
Description: Positive allosteric modulation of human muscarinic M4 receptor expressed in CHO cells co-expressing Gqi5 assessed as increase in acetylcholine-induced calcium mobilization relative to acetylcholine
Format: BAO_0000219
Organism: Homo sapiens
Cell type: CHO
Target: Muscarinic acetylcholine receptor M4(ALA1821)
Document: ALA4610000
Positive allosteric modulation of human muscarinic M4 receptor expressed in CHO cells co-expressing Gqi5 assessed as increase in acetylcholine-induced calcium mobilization relative to acetylcholine: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4610690
%max
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 267.34 | 2.43 | 2.43 |
| 405.29 | 2.78 | 2.78 |
| 382.82 | 1.09 | 1.09 |
| 416.53 | 4.21 | 4.21 |
| 409.88 | 3.18 | 3.18 |
| 268.36 | 3.41 | 3.41 |
| 395.85 | 2.00 | 2.00 |
| 396.84 | 2.27 | 2.27 |
| 351.39 | 3.58 | 3.58 |
| 361.45 | 3.66 | 3.66 |
| 358.35 | 1.45 | 1.45 |
| 400.49 | 3.72 | 3.72 |
| 370.84 | 2.13 | 2.13 |
| 295.35 | 1.66 | 1.66 |
| 388.83 | 2.27 | 2.27 |
| 355.38 | 1.01 | 1.01 |
| 268.32 | 2.27 | 2.27 |
| 400.87 | 2.14 | 2.14 |
| 375.80 | 1.36 | 1.36 |
| 354.39 | 1.62 | 1.62 |
| 339.35 | 3.72 | 3.72 |
| 401.26 | 2.91 | 2.91 |
| 363.46 | 3.66 | 3.66 |
| 404.40 | 2.50 | 2.50 |
| 371.39 | 2.36 | 2.36 |
| 414.30 | 3.83 | 3.83 |
| 414.51 | 4.11 | 4.11 |
| 338.35 | 2.67 | 2.67 |
| 387.83 | 1.23 | 1.23 |
| 391.36 | 1.58 | 1.58 |
| 357.81 | 1.22 | 1.22 |
| 348.37 | 0.44 | 0.44 |
| 392.25 | 1.87 | 1.87 |
| 348.41 | 2.75 | 2.75 |
| 375.80 | 1.36 | 1.36 |
| 281.36 | 3.18 | 3.18 |