Basic Information
ID: ALA4610865
Type: Binding
Description: Inhibition of SMO-mediated Hedgehog signaling pathway in mouse C3H10T1/2 cells assessed as reduction in sonic hedgehog-induced osteoblast differentiation by measuring alkaline phosphatase activity incubated for 72 hrs
Organism: Mus musculus
Cell type: C3H 10T1/2
Activity Charts
Bioactivity
Activity Types for Assay ALA4610865
EC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 421.31 | 4.71 | 4.71 |
| 384.44 | 4.61 | 4.61 |
| 398.47 | 4.62 | 4.62 |
| 384.44 | 4.61 | 4.61 |
| 398.47 | 4.62 | 4.62 |
| 398.47 | 4.92 | 4.92 |
| 398.47 | 4.92 | 4.92 |
| 412.49 | 4.93 | 4.93 |
| 398.47 | 4.92 | 4.92 |
| 402.43 | 4.75 | 4.75 |
| 432.91 | 5.28 | 5.28 |
| 446.94 | 5.58 | 5.58 |
| 448.53 | 6.07 | 6.07 |
| 412.49 | 4.93 | 4.93 |
| 424.50 | 5.17 | 5.17 |
| 412.49 | 4.93 | 4.93 |
| 398.47 | 4.92 | 4.92 |
| 429.55 | 5.96 | 5.96 |
| 412.49 | 5.23 | 5.23 |
| 432.91 | 5.28 | 5.28 |
| 418.88 | 5.26 | 5.26 |
| 424.50 | 5.17 | 5.17 |
| 409.49 | 5.59 | 5.59 |
| 409.49 | 5.59 | 5.59 |
| 425.49 | 4.57 | 4.57 |
| 440.55 | 5.55 | 5.55 |
| 412.49 | 5.23 | 5.23 |