Basic Information
ID: ALA4610875
Type: Functional
Description: Inhibition of GLI mRNA expression in mouse xenografted with human COLO205 cells at 40 mg/kg, po administered as single dose measured after 8 hrs by RT-PCR analysis relative to control
Organism: Mus musculus
Cell type: COLO 205
Activity Charts
Bioactivity
Activity Types for Assay ALA4610875
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 421.31 | 4.71 | 4.71 |
| 384.44 | 4.61 | 4.61 |
| 398.47 | 4.62 | 4.62 |
| 398.47 | 4.92 | 4.92 |
| 402.43 | 4.75 | 4.75 |
| 412.49 | 4.93 | 4.93 |
| 412.49 | 4.93 | 4.93 |
| 398.47 | 4.92 | 4.92 |
| 412.49 | 5.23 | 5.23 |
| 425.49 | 4.57 | 4.57 |
| 412.49 | 5.23 | 5.23 |