Inhibition of human His6-tagged NOTUM (81 to 451 residues) Cys330Ser mutant transfected in HEK293S cells using OPTS as substrate incubated for 1 hr by...

Basic Information

ID: ALA4610952

Type: Binding

Description: Inhibition of human His6-tagged NOTUM (81 to 451 residues) Cys330Ser mutant transfected in HEK293S cells using OPTS as substrate incubated for 1 hr by fluorescence based assay

Format: BAO_0000219

Organism: Homo sapiens

Target: Palmitoleoyl-protein carboxylesterase NOTUM(ALA3714531)

Document: ALA4610015

Inhibition of human His6-tagged NOTUM (81 to 451 residues) Cys330Ser mutant transfected in HEK293S cells using OPTS as substrate incubated for 1 hr by fluorescence based assay: 1

Associated Items: Associated Bioactivities Associated Compounds

Activity Charts

Bioactivity

Activity Types for Assay ALA4610952

IC50

Total(50)

Compound Summary

Parent Molecular Weight	ALogP	Polar Surface Area
254.34	2.48	2.48
240.31	2.18	2.18
209.23	1.13	1.13
274.75	2.83	2.83
300.79	3.40	3.40
292.34	3.56	3.56
390.41	2.37	2.37
336.44	1.66	1.66
291.36	2.62	2.62
374.34	1.90	1.90
243.68	1.79	1.79
394.91	2.69	2.69
424.86	2.94	2.94
343.86	2.60	2.60
370.89	2.09	2.09
223.26	1.14	1.14
238.27	2.02	2.02
394.91	2.69	2.69
384.91	2.44	2.44
390.41	2.37	2.37
406.92	2.95	2.95
292.24	2.73	2.73
384.91	2.48	2.48
370.89	2.39	2.39
341.89	3.76	3.76
448.88	3.40	3.40
408.94	2.94	2.94
396.93	2.58	2.58
382.90	2.27	2.27
380.89	2.38	2.38
238.27	0.85	0.85
265.32	2.05	2.05
356.86	1.70	1.70
308.31	3.20	3.20
420.95	3.26	3.26
380.89	2.38	2.38
268.36	2.79	2.79
308.31	3.20	3.20
368.87	2.23	2.23
448.88	3.40	3.40
382.90	2.54	2.54
367.93	4.33	4.33
369.90	3.17	3.17
356.86	2.00	2.00
327.86	3.40	3.40
299.36	2.66	2.66
370.89	2.05	2.05
342.83	1.66	1.66
382.90	2.57	2.57
301.82	2.83	2.83