Basic Information
ID: ALA4610952
Type: Binding
Description: Inhibition of human His6-tagged NOTUM (81 to 451 residues) Cys330Ser mutant transfected in HEK293S cells using OPTS as substrate incubated for 1 hr by fluorescence based assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4610952
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 254.34 | 2.48 | 2.48 |
| 240.31 | 2.18 | 2.18 |
| 209.23 | 1.13 | 1.13 |
| 274.75 | 2.83 | 2.83 |
| 300.79 | 3.40 | 3.40 |
| 292.34 | 3.56 | 3.56 |
| 390.41 | 2.37 | 2.37 |
| 336.44 | 1.66 | 1.66 |
| 291.36 | 2.62 | 2.62 |
| 374.34 | 1.90 | 1.90 |
| 243.68 | 1.79 | 1.79 |
| 394.91 | 2.69 | 2.69 |
| 424.86 | 2.94 | 2.94 |
| 343.86 | 2.60 | 2.60 |
| 370.89 | 2.09 | 2.09 |
| 223.26 | 1.14 | 1.14 |
| 238.27 | 2.02 | 2.02 |
| 394.91 | 2.69 | 2.69 |
| 384.91 | 2.44 | 2.44 |
| 390.41 | 2.37 | 2.37 |
| 406.92 | 2.95 | 2.95 |
| 292.24 | 2.73 | 2.73 |
| 384.91 | 2.48 | 2.48 |
| 370.89 | 2.39 | 2.39 |
| 341.89 | 3.76 | 3.76 |
| 448.88 | 3.40 | 3.40 |
| 408.94 | 2.94 | 2.94 |
| 396.93 | 2.58 | 2.58 |
| 382.90 | 2.27 | 2.27 |
| 380.89 | 2.38 | 2.38 |
| 238.27 | 0.85 | 0.85 |
| 265.32 | 2.05 | 2.05 |
| 356.86 | 1.70 | 1.70 |
| 308.31 | 3.20 | 3.20 |
| 420.95 | 3.26 | 3.26 |
| 380.89 | 2.38 | 2.38 |
| 268.36 | 2.79 | 2.79 |
| 308.31 | 3.20 | 3.20 |
| 368.87 | 2.23 | 2.23 |
| 448.88 | 3.40 | 3.40 |
| 382.90 | 2.54 | 2.54 |
| 367.93 | 4.33 | 4.33 |
| 369.90 | 3.17 | 3.17 |
| 356.86 | 2.00 | 2.00 |
| 327.86 | 3.40 | 3.40 |
| 299.36 | 2.66 | 2.66 |
| 370.89 | 2.05 | 2.05 |
| 342.83 | 1.66 | 1.66 |
| 382.90 | 2.57 | 2.57 |
| 301.82 | 2.83 | 2.83 |