Basic Information
ID: ALA4610953
Type: Binding
Description: Inhibition of NOTUM (unknown origin) transfected in human HEK293T cells harbouring TCF/LEF luciferase reporter gene assessed as activation of Wnt signalling pathway incubated for 10 mins followed by wnt-3A addition and further incubated for 1 hr by steady-glo luciferase assay
Format: BAO_0000219
Organism: Homo sapiens
Cell type: HEK-293T
Target: Palmitoleoyl-protein carboxylesterase NOTUM(ALA3714531)
Document: ALA4610015
Inhibition of NOTUM (unknown origin) transfected in human HEK293T cells harbouring TCF/LEF luciferase reporter gene assessed as activation of Wnt signalling pathway incubated for 10 mins followed by wnt-3A addition and further incubated for 1 hr by steady-glo luciferase assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4610953
EC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 390.41 | 2.37 | 2.37 |
| 336.44 | 1.66 | 1.66 |
| 374.34 | 1.90 | 1.90 |
| 390.41 | 2.37 | 2.37 |
| 382.90 | 2.57 | 2.57 |