Agonist activity at TLR7 in human PBMC cells assessed as immunostimulatory activity by measuring fold increase in TNFalpha secretion at 10 uM incubate...

Basic Information

ID: ALA4611055

Type: Binding

Description: Agonist activity at TLR7 in human PBMC cells assessed as immunostimulatory activity by measuring fold increase in TNFalpha secretion at 10 uM incubated for 18 hrs by ELISA relative to 1V209

Format: BAO_0000219

Organism: Homo sapiens

Cell type: PBMC

Target:  Toll-like receptor 7(ALA5936)

Document:  ALA4610021

Agonist activity at TLR7 in human PBMC cells assessed as immunostimulatory activity by measuring fold increase in TNFalpha secretion at 10 uM incubated for 18 hrs by ELISA relative to 1V209: 1

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
1311.21
520.50-2.28-2.28
682.64-4.46-4.46