Basic Information
ID: ALA4611266
Type: Binding
Description: Antagonist activity at Prolink-tagged human CXCR6 receptor assessed as inhibition of CXCL16-induced beta-arrestin recruitment by DiscoveRx cell based assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4611266
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 499.61 | 4.78 | 4.78 |
| 492.58 | 3.34 | 3.34 |
| 480.63 | 5.24 | 5.24 |
| 458.99 | 4.68 | 4.68 |
| 454.57 | 4.04 | 4.04 |
| 502.01 | 4.12 | 4.12 |
| 463.58 | 4.51 | 4.51 |
| 536.46 | 4.77 | 4.77 |
| 511.64 | 4.65 | 4.65 |
| 377.49 | 3.44 | 3.44 |
| 549.62 | 5.66 | 5.66 |
| 474.60 | 5.18 | 5.18 |
| 495.65 | 4.68 | 4.68 |
| 467.57 | 3.47 | 3.47 |
| 495.62 | 4.08 | 4.08 |
| 516.06 | 5.29 | 5.29 |
| 502.01 | 4.12 | 4.12 |
| 560.51 | 5.40 | 5.40 |
| 495.62 | 4.08 | 4.08 |
| 495.65 | 4.95 | 4.95 |
| 535.56 | 4.49 | 4.49 |
| 485.56 | 3.61 | 3.61 |
| 497.59 | 3.48 | 3.48 |
| 516.06 | 5.29 | 5.29 |
| 546.46 | 4.23 | 4.23 |
| 481.59 | 3.77 | 3.77 |
| 458.99 | 4.68 | 4.68 |
| 475.59 | 4.58 | 4.58 |
| 516.06 | 5.29 | 5.29 |
| 481.62 | 4.64 | 4.64 |
| 454.57 | 4.04 | 4.04 |
| 465.55 | 4.17 | 4.17 |
| 485.56 | 3.61 | 3.61 |
| 471.99 | 4.11 | 4.11 |
| 455.94 | 3.82 | 3.82 |
| 485.56 | 3.61 | 3.61 |
| 497.59 | 3.48 | 3.48 |
| 458.99 | 4.68 | 4.68 |
| 463.58 | 4.51 | 4.51 |
| 539.63 | 3.64 | 3.64 |
| 441.96 | 4.10 | 4.10 |
| 441.96 | 4.10 | 4.10 |
| 546.46 | 4.23 | 4.23 |
| 464.57 | 3.68 | 3.68 |
| 427.50 | 2.55 | 2.55 |
| 502.01 | 4.12 | 4.12 |
| 464.57 | 3.90 | 3.90 |
| 516.06 | 5.29 | 5.29 |
| 497.59 | 3.48 | 3.48 |
| 536.46 | 4.77 | 4.77 |
| 536.46 | 4.77 | 4.77 |
| 536.46 | 4.77 | 4.77 |
| 471.99 | 4.11 | 4.11 |
| 481.59 | 3.77 | 3.77 |
| 467.57 | 3.47 | 3.47 |
| 481.59 | 3.77 | 3.77 |
| 536.46 | 4.77 | 4.77 |
| 454.57 | 4.04 | 4.04 |
| 453.54 | 3.08 | 3.08 |
| 509.63 | 4.32 | 4.32 |
| 536.46 | 4.77 | 4.77 |