Basic Information
ID: ALA4611684
Type: Binding
Description: Selectivity index, ratio of IC50 for displacement of [125I]-ghrelin from human GHS-R1a stably expressed in HEK cell membrane measured after 60 mins by gamma counter method to EC50 for agonist activity at human GPR81 overexpressed in CHO cells assessed as inhibition of forskolin-stimulated cAMP production
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4611684
Ratio IC50/EC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 622.21 | 3.85 | 3.85 |
| 650.27 | 4.63 | 4.63 |
| 579.14 | 4.31 | 4.31 |
| 417.92 | 4.44 | 4.44 |
| 650.27 | 4.63 | 4.63 |
| 530.09 | 4.18 | 4.18 |
| 531.08 | 4.91 | 4.91 |
| 636.24 | 4.24 | 4.24 |