Basic Information
ID: ALA4612143
Type: Binding
Description: Inhibition of recombinant human PTP1B (1 to 321 residues) expressed in Escherichia coli at 10 uM using p-nitrophenyl phosphate as substrate incubated for 30 mins relative to control
Format: BAO_0000019
Organism: Homo sapiens
Target: Protein-tyrosine phosphatase 1B(ALA335)
Document: ALA4610094
Inhibition of recombinant human PTP1B (1 to 321 residues) expressed in Escherichia coli at 10 uM using p-nitrophenyl phosphate as substrate incubated for 30 mins relative to control: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4612143
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 270.24 | 2.58 | 2.58 |
| 254.24 | 2.87 | 2.87 |
| 286.24 | 2.28 | 2.28 |
| 256.26 | 2.70 | 2.70 |
| 284.27 | 2.88 | 2.88 |
| 270.28 | 3.00 | 3.00 |
| 314.29 | 2.89 | 2.89 |
| 310.35 | 4.73 | 4.73 |
| 408.49 | 5.53 | 5.53 |
| 380.40 | 4.92 | 4.92 |
| 272.30 | 2.83 | 2.83 |
| 322.36 | 4.18 | 4.18 |
| 340.38 | 4.73 | 4.73 |
| 354.36 | 3.79 | 3.79 |
| 368.39 | 4.09 | 4.09 |
| 370.45 | 4.34 | 4.34 |
| 352.34 | 3.76 | 3.76 |
| 424.49 | 4.89 | 4.89 |
| 422.48 | 5.30 | 5.30 |
| 354.40 | 5.04 | 5.04 |
| 354.36 | 3.79 | 3.79 |
| 336.34 | 4.06 | 4.06 |
| 438.56 | 5.85 | 5.85 |
| 440.49 | 3.99 | 3.99 |
| 354.40 | 3.97 | 3.97 |
| 454.56 | 4.82 | 4.82 |
| 438.52 | 5.19 | 5.19 |
| 352.39 | 4.92 | 4.92 |
| 420.51 | 5.70 | 5.70 |
| 354.40 | 5.04 | 5.04 |
| 438.48 | 3.96 | 3.96 |
| 340.42 | 4.33 | 4.33 |
| 370.40 | 3.68 | 3.68 |
| 370.40 | 3.68 | 3.68 |
| 354.36 | 3.35 | 3.35 |
| 340.38 | 4.02 | 4.02 |