Basic Information
ID: ALA4612473
Type: Binding
Description: Inhibition of SERCA1 in rat INS-1E cells assessed as induction of apoptosis by measuring increase in late apoptotic cells at IC50 for cell viability incubated for 24 hrs by Annexin V-FITC/propidium iodide staining based flow cytometry
Format: BAO_0000219
Organism: Rattus norvegicus
Target: Sarcoplasmic/endoplasmic reticulum calcium ATPase 1(ALA3585236)
Document: ALA4610111
Inhibition of SERCA1 in rat INS-1E cells assessed as induction of apoptosis by measuring increase in late apoptotic cells at IC50 for cell viability incubated for 24 hrs by Annexin V-FITC/propidium iodide staining based flow cytometry: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4612473
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 326.35 | 3.59 | 3.59 |
| 326.35 | 3.59 | 3.59 |
| 420.46 | 5.27 | 5.27 |
| 438.52 | 5.75 | 5.75 |
| 424.49 | 5.45 | 5.45 |
| 558.54 | 7.26 | 7.26 |
| 562.57 | 7.10 | 7.10 |