Basic Information
ID: ALA4612962
Type: Binding
Description: Inhibition of recombinant human N-terminal His6-tagged DCLK1 (G351 to H689 residues) expressed in Escherichia coli BL21 DE3 using 5-FAM-KKLRRTLSVA-COOH as substrate measured after 2 hrs by mobility shift assay
Format: BAO_0000019
Organism: Homo sapiens
Target: Serine/threonine-protein kinase DCLK1(ALA5683)
Document: ALA4610122
Inhibition of recombinant human N-terminal His6-tagged DCLK1 (G351 to H689 residues) expressed in Escherichia coli BL21 DE3 using 5-FAM-KKLRRTLSVA-COOH as substrate measured after 2 hrs by mobility shift assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4612962
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 445.53 | 3.31 | 3.31 |
| 459.55 | 3.34 | 3.34 |
| 460.54 | 3.55 | 3.55 |
| 446.51 | 3.42 | 3.42 |
| 445.53 | 3.00 | 3.00 |
| 474.57 | 3.94 | 3.94 |
| 410.46 | 2.23 | 2.23 |
| 501.59 | 3.41 | 3.41 |
| 473.58 | 3.73 | 3.73 |
| 487.61 | 4.12 | 4.12 |
| 513.65 | 4.65 | 4.65 |
| 473.58 | 3.65 | 3.65 |
| 494.00 | 3.99 | 3.99 |
| 494.00 | 3.99 | 3.99 |
| 638.82 | 5.14 | 5.14 |
| 410.46 | 2.23 | 2.23 |
| 488.59 | 4.33 | 4.33 |
| 444.54 | 3.85 | 3.85 |
| 473.58 | 3.73 | 3.73 |
| 482.57 | 3.74 | 3.74 |
| 499.62 | 4.26 | 4.26 |
| 454.51 | 2.96 | 2.96 |
| 473.58 | 3.65 | 3.65 |
| 527.55 | 4.27 | 4.27 |
| 569.59 | 4.34 | 4.34 |
| 522.51 | 3.89 | 3.89 |
| 515.62 | 3.80 | 3.80 |
| 468.54 | 3.35 | 3.35 |
| 541.58 | 4.58 | 4.58 |
| 535.65 | 4.91 | 4.91 |
| 555.61 | 5.05 | 5.05 |
| 424.49 | 2.95 | 2.95 |
| 529.65 | 4.19 | 4.19 |
| 570.70 | 3.44 | 3.44 |
| 542.69 | 3.80 | 3.80 |
| 501.64 | 4.51 | 4.51 |
| 487.61 | 4.12 | 4.12 |
| 430.51 | 3.54 | 3.54 |