Basic Information
ID: ALA4612964
Type: Binding
Description: Inhibition of ERK5 in human HeLa cells assessed as reduction in EGF-induced ERK5 autophosphorylation pretreated for 1 hr followed by EGF stimulation and measured after 17 mins by 32p kinase assay
Organism: Homo sapiens
Cell type: HeLa
Activity Charts
Bioactivity
Activity Types for Assay ALA4612964
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 445.53 | 3.31 | 3.31 |
| 459.55 | 3.34 | 3.34 |
| 501.59 | 3.41 | 3.41 |
| 473.58 | 3.73 | 3.73 |
| 487.61 | 4.12 | 4.12 |
| 513.65 | 4.65 | 4.65 |
| 473.58 | 3.65 | 3.65 |
| 494.00 | 3.99 | 3.99 |
| 494.00 | 3.99 | 3.99 |
| 473.58 | 3.73 | 3.73 |
| 499.62 | 4.26 | 4.26 |
| 454.51 | 2.96 | 2.96 |
| 473.58 | 3.65 | 3.65 |
| 527.55 | 4.27 | 4.27 |
| 515.62 | 3.80 | 3.80 |
| 501.64 | 4.51 | 4.51 |