Basic Information
ID: ALA4612975
Type: Functional
Description: Antagonist activity at human CGRP receptor in human SK-N-MC cells assessed as inhibition of CGRP-induced cAMP production preincubated for 30 mins followed by CGRP addition and measured after 30 mins by HTRF assay
Organism: Homo sapiens
Cell type: SK-N-MC
Activity Charts
Bioactivity
Activity Types for Assay ALA4612975
pKb
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 869.66 | 4.41 | 4.41 |
| 763.90 | 3.06 | 3.06 |
| 882.66 | 3.53 | 3.53 |
| 756.87 | 2.73 | 2.73 |
| 762.92 | 2.49 | 2.49 |
| 736.88 | 2.22 | 2.22 |
| 775.96 | 3.62 | 3.62 |
| 772.96 | 3.83 | 3.83 |
| 895.70 | 4.67 | 4.67 |