Basic Information
ID: ALA4613052
Type: Binding
Description: Inhibition of HIF1 transactivation activity in HEK293T cells transfected with pGL3-5HRE-VEGF-luciferase at 0.01 to 1 uM incubated for 24 hrs under hypoxia condition by luciferase reporter gene assay
Format: BAO_0000219
Organism: Homo sapiens
Cell type: HEK-293T
Target: Unchecked(ALA612545)
Document: ALA4610125
Inhibition of HIF1 transactivation activity in HEK293T cells transfected with pGL3-5HRE-VEGF-luciferase at 0.01 to 1 uM incubated for 24 hrs under hypoxia condition by luciferase reporter gene assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4613052
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 732.87 | 7.82 | 7.82 |
| 706.79 | 8.37 | 8.37 |
| 714.81 | 8.02 | 8.02 |
| 656.73 | 7.21 | 7.21 |
| 700.78 | 7.63 | 7.63 |
| 696.79 | 8.13 | 8.13 |
| 707.78 | 7.77 | 7.77 |
| 739.86 | 8.10 | 8.10 |
| 714.81 | 7.88 | 7.88 |
| 699.80 | 7.20 | 7.20 |
| 776.97 | 8.39 | 8.39 |